One of the best herbs for mood elevation is St. John's wort. Several controlled studies have shown positive results in treating patients with mild to moderate depression. Improvement was shown with symptoms of sadness, helplessness, hopelessness, anxiety, headache and exhaustion with no reported side effects. Its action is based on the ability of the active ingredient, hypericin to inhibit the breakdown of neurotransmitters in the brain. The herb also inhibits monoamine oxidase (MAO) and works as a serotonin reuptake inhibitor (SRI); both are actions similar to drugs prescribed for depression. In Germany, nearly half of depression, anxiety, and sleep disorders are treated with hypericin. St. John's wort should not be taken with any other antidepressants. Dose is 300mg 3x a day with food. Not to be taken with prescription medications. Can be taken with amino acids including 5HTP. |