(pronounced 'sa-me' as in the name 'Sammy') has been hailed as the safest and most effective natural antidepressant ever used. The full name is S-adenosyl-methionine and it is a molecule derived from the union of the amino acid methionine to a factor responsible for energy production, called adenosine triphosphate (ATP). SAMe increases the action of several neurotransmitters (dopamine, serotonin and norepinephrine for example) by facilitating the binding of these hormones to their cell receptors. SAMe has been shown through several well designed studies to be one of the best natural antidepressants available. There have been more than 100 peer-reviewed studies showing that SAMe is an effective natural medication for depression. It's faster-acting with fewer side effects than prescription anti-depressants. It also helps increase the production of endorphins. Endorphins are the bodies natural pain blocking chemicals and are more powerful than morphine. SAMe helps manufacture and repair cartilage components. A study of osteoarthritis patients compared SAMe with NSAID drugs in its ability to reduce pain. One double-blind study showed SAMe was superior to ibuprofen in the treatment of osteoarthritis. Several studies involving SAMe and fibromyalgia patients yielded substantial improvement in over all pain levels (as well as depression). The dosage of SAMe is between 200mg to 800mg a day on an empty stomach. Don't take past 3 P.M. |