This test determines if a person has Leaky Gut Syndrome. Leaky Gut Syndrome is associated with allergies, pain, inflammation, Crohn's disease, and other illnesses. The small intestine has the paradoxical dual function of being a digestive/ absorptive organ for nutrients as well as a powerful barrier against the excessive absorption of bacteria, food antigens and large molecules. Increased permeability of the intestinal mucosal barrier can swell the number of toxins & antigens entering the bloodstream and lead to an overly sensitized immune system in some individuals. Decreased permeability, on the other hand, appears as a fundamental cause of malnutrition, malabsorption and failure to thrive. A number of clinical disorders are associated with both conditions. The Intestinal Permeability Assessment directly measures the ability of two nonmetabolized sugar molecules –mannitol and lactulose–to permeate the intestinal mucosa. Mannitol is easily absorbed and serves as a marker of transcellular uptake, while lactulose is only slightly absorbed and serves as a marker for mucosal integrity. To perform the test, the patient mixes premeasured amounts of lactulose and mannitol and drinks the challenge substance. The test measures the amount of lactulose and mannitol recovered in a urine sample over the next 6 hours. NOTE: NEW YORK STATE DOES NOT ALLOW SHIPMENT OF THESE TESTS INTO THE STATE. Test - Leaky Gut - Intestinal Permeability Assessment ipt$123.00 Application Guide Frequently Asked Questions Search for: